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Comparison of plasma and urine analyses for thiazides in bioavailability/bioequivalence study

✍ Scribed by Vinod P. Shah; John P. Hunt; Vadlamani K. Prasad; Bernard E. Cabana


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
386 KB
Volume
70
Category
Article
ISSN
0022-3549

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## Abstract A rapid, simple and validated liquid chromatography coupled to tandem mass spectrometric method (LC‐MS/MS) for topiramate analysis in human plasma has been applied to pharmacokinetic and bioequivalence studies in 24 healthy male Korean volunteers. The procedure involves a simple liquid