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Comparison of optimization methods for fed-batch cultures of hybridoma cells

✍ Scribed by Roubos, J. A.; de Gooijer, C. D.; van Straten, G.; van Boxtel, A. J. B.

Book ID
113044153
Publisher
Springer
Year
1997
Tongue
English
Weight
190 KB
Volume
17
Category
Article
ISSN
1615-7605

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## Abstract The achievement of high cell density and monoclonal antibody concentration depends on understanding cell metabolism and the control of cell culture. A model of cell metabolism and monoclonal antibody production in hybridoma cell culture is presented. Fed‐batch culture in serum‐free medi