Comparison of nuclear 5α-reductase activities in the stromal and epithelial fractions of human prostatic tissue
✍ Scribed by Robert W. Hudson
- Book ID
- 116006178
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 572 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-4731
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
BACKGROUND. Steroid 5a-reductase is essential for the intracellular accumulation of dihydrotestosterone (DHT), which mediates androgen effects on target tissue. METHODS. In the present study, we describe the differential expression and cellular localization of 5a-reductase 1 and 2 isoenzymes in the
BACKGROUND. Prostate trophism depends on DHT formed from T by the enzyme 5␣-R. Two 5␣-R isoforms with different biochemical characteristics have been cloned. Also estrogens might contribute to the prostate growth; however, their intraglandular formation by the enzyme aromatase is still debated. The