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Comparison of microbiologically and enzymatically mediated Baeyer?Villiger oxidations: synthesis of optically active caprolactones

✍ Scribed by Alphand, V�ronique; Furstoss, Roland; Pedragosa-Moreau, Sandrine; Roberts, Stanley M.; Willetts, Andrew J.


Book ID
119967698
Publisher
Royal Society of Chemistry
Year
1996
Weight
771 KB
Volume
15
Category
Article
ISSN
1472-7781

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## Abstract Racemic and enantiomerically enriched methyl 2‐siloxycyclopropanecarboxylates 1 have been ring‐opened to furnish γ‐oxo esters 2. Depending on the electronic properties of substituents, these could be transformed into either succinate derivatives 3 or 3‐oxybutanoates 4 by Baeyer‐Villiger