𝔖 Bobbio Scriptorium
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Comparison of metrizamide and iodophendylate for cerebral ventriculography

✍ Scribed by A. Gjerris; J. Præstholm; L. Klinken

Book ID
104727168
Publisher
Springer
Year
1978
Tongue
English
Weight
679 KB
Volume
15
Category
Article
ISSN
0028-3940

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✦ Synopsis

Cerebral ventriculography was performed on adult albino rats to compare the effect of metrizamide and iodophendylate on the ependymal wall. The animals were killed by vascular perfusion 1 month and 4 months after ventriculography. The ependymal layer and the underlying brain tissue were examined with the electron microscope. After the use of metrizamide the tissue appeared completely normal. The use of iodophendylate provoked accumulation of phagocytozing macrophages on the ependymal wall and storage of iodophendylate in the ependyma and underlying brain tissue. These changes were present both 1 and 4 months after ventriculography.

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