## Abstract Improved methods to increase surface hardness of metallic biomedical implants are being developed in an effort to minimize the formation of wear debris particles that cause local pain and inflammation. However, for many implant surface treatments, there is a risk of film delamination du
Comparison of mesenchymal stem cell and osteosarcoma cell adhesion to hydroxyapatite
β Scribed by Shikhar Vohra; Kristin M. Hennessy; Amber A. Sawyer; Ya Zhuo; Susan L. Bellis
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 370 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0957-4530
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## Abstract Modification of the chemistry and surface topography of nanophase ceramics was used to provide biomaterial formulations designed to direct the adhesion and proliferation of human mesenchymal stem cells (HMSCs). HMSC adhesion was dependent upon both the substrate chemistry and grain size
## Abstract Osteoinductivity of hydroxyapatite (HA) was investigated using uncommitted pluripotent mouse stem cells, C3H10T1/2 in an __in vitro__ differentiation assay. For comparative analysis, the cells were cultured on substrates made of osteoinductive HA, with biocompatible titanium and plastic
## Abstract Mesenchymal stem cells (MSCs) are a heterogeneous population of stem/progenitor cells with pluripotent capacity to differentiate into mesodermal and nonβmesodermal cell lineages, including osteocytes, adipocytes, chondrocytes, myocytes, cardiomyocytes, fibroblasts, myofibroblasts, epith