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Comparison of meclizine levels in the plasma of rats and dogs after intranasal, intravenous, and oral administration

✍ Scribed by James P. Chovan; Robert P. Klett; Nathan Rakieten

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
297 KB
Volume
74
Category
Article
ISSN
0022-3549

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Pharmacokinetics of ethopropazine in the
Pharmacokinetics of ethopropazine in the rat after oral and intravenous administration
✍ Mojdeh Maboudian-Esfahani; Dion R. Brocks πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 115 KB πŸ‘ 2 views

The pharmacokinetics of the anticholinergic drug ethopropazine (ET) have been studied in the rat after intravenous (i.v.) and oral administration. After i.v. doses of 5 and 10 mg/kg ET HCl, mean +/- S.D. plasma AUC were 9836 +/- 2129 (n = 4 rats) and 13096 +/- 4186 ng h/mL (n = 5 rats), respectively