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Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains

✍ Scribed by Julia A Tree; Catherine Richardson; Anthony R Fooks; J.Christopher Clegg; Denis Looby


Book ID
117430352
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
130 KB
Volume
19
Category
Article
ISSN
0264-410X

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## Abstract A process scheme for the harvesting and concentration of cell culture‐derived human influenza A virus is presented. The scheme comprises two static filtration steps, chemical inactivation by β‐propiolactone and cross‐flow ultrafiltration. Human influenza A virus A/PR/8/34 (H1N1) was pro