Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides

Inhibition of forskolin-stimulated cAMP

Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult rats

✍ Kenneth Olivier Jr.; Jing Liu; Carey Pope 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB

## Abstract Parathion (PS) and chlorpyrifos (CPF) are organophosphorus insecticides, which elicit toxicity following biotransformation to the potent acetylcholinesterase inhibitors, paraoxon (PO) and chlorpyrifos oxon (CPO). Both oxons have also been shown to interact directly with muscarinic recep