In this study, the upper-limit volume (gas plus partial tissue volume) as well as absolute volume (gas only) of lungs measured with hyperpolarized (3)He-MR imaging is compared with that determined by micro-computed tomography (CT) under similar ventilation conditions in normal rats. Five Brown Norwa
Comparison of hyperpolarized 3He MRI with Xe-enhanced computed tomography imaging for ventilation mapping of rat lung
β Scribed by Giles E. Santyr; Marcus J. Couch; Wilfred W. Lam; Alexei Ouriadov; Maria Drangova; David G. McCormack; David W. Holdsworth
- Book ID
- 102957751
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 760 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1659
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## Abstract Images of hyperpolarized ^3^He were acquired during breathβhold in four healthy volunteers with the use of an optimized 3D gradientβecho sequence. The images were compared with existing 2D gradientβecho methods. The average SNR from a 13βmmβthick slice in the peripheral lung was 1.4 tim
## Abstract A novel imaging method is presented, Flip Angle Variation for Offset of RF and Relaxation (FAVOR), for rapid and efficient measurement of rat lung ventilation using hyperpolarized heliumβ3 (^3^He) gas. The FAVOR technique utilizes variable flip angles to remove the cumulative effect of