𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene–treated Big Blue® rats

✍ Scribed by Tao Chen; Roberta A. Mittelstaedt; Anane Aidoo; L. Patrice Hamilton; Frederick A. Beland; Daniel A. Casciano; Robert H. Heflich

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
115 KB
Volume
37
Category
Article
ISSN
0893-6692

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Gene- and tissue-specificity of mutation
Gene- and tissue-specificity of mutation in Big Blue® rats treated with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene
✍ Tao Chen; Roberta A. Mittelstaedt; Sharon D. Shelton; S. Balachandra Dass; Mugim 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB

In a previous study, we found that treating transgenic Big Blue rats with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene (N-OH-AAF) produced the same major DNA adduct in the target liver and the nontarget spleen lymphocytes and bone marrow cells, induced lacI mutants in the liver, and induced