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Comparison of half-disappearance times, distribution volumes and metabolic clearance rates of exogenous glucagon-like peptide 1 and glucagon in rats

✍ Scribed by Ichiyo Oshima; Meisei Hirota; Chizuko Ohboshi; Kenji Shima


Book ID
118398016
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
435 KB
Volume
21
Category
Article
ISSN
0167-0115

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Cassette dosing for pharmacokinetic scre
✍ Rakesh Nagilla; Melanie Nord; Jeff J. Mcatee; Larry J. Jolivette πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 447 KB

The purpose of this investigation was to compare selected pharmacokinetic (PK) parameters obtained by cassette and discrete dosing of compounds in rats. The concordance of PK properties obtained by the two dosing strategies was evaluated for 116 compounds representing various therapeutic programs an