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Comparison of genetic variation of breast cancer susceptibility genes in Chinese and German populations

✍ Scribed by Barzan, David; Veldwijk, Marlon R; Herskind, Carsten; Li, Yang; Zhang, Bo; Sperk, Elena; Du, Wei-Dong; Zhang, Xue-Jun; Wenz, Frederik

Book ID: 120031356
Publisher: Nature Publishing Group
Year: 2013
Tongue: English
Weight: 307 KB
Volume: 21
Category: Article
ISSN: 1018-4813
DOI: 10.1038/ejhg.2013.38

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## Abstract Germline mutations in the tumor suppressor gene __TP53__ are associated with high incidence of early‐onset malignancies, and somatic mutations occur in 20–40% of all breast cancer cases. We investigated the association of common genetic variation in __TP53__ and its flanking genes, __WD