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Comparison of gene expression of extracellular matrix molecules in brain microvascular endothelial cells and astrocytes

✍ Scribed by G. Webersinke; H. Bauer; A. Amberger; O. Zach; H.C. Bauer

Book ID
115765732
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
587 KB
Volume
189
Category
Article
ISSN
0006-291X

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## Abstract Matrix metalloproteinase‐13 (MMP‐13) is involved in the degradation of extracellular matrix in many kinds of tissues. Here we found that hypoxia increased MMP‐13 protein and mRNA levels in primary rat astrocyte cultures. Hypoxia stimulation also increased the secretion of MMP‐13 from as