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Comparison of Gene Expression in Male and Female Mouse Blastocysts Revealed Imprinting of the X-Linked Gene, Rhox5/Pem, at Preimplantation Stages

✍ Scribed by Shin Kobayashi; Ayako Isotani; Nathan Mise; Masamichi Yamamoto; Yoshitaka Fujihara; Kazuhiro Kaseda; Tomoko Nakanishi; Masahito Ikawa; Hiroshi Hamada; Kuniya Abe; Masaru Okabe


Book ID
113559822
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
439 KB
Volume
16
Category
Article
ISSN
0960-9822

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The potentially unbalanced expression at preimplantation developmental stages of Xlinked genes might be responsible of the faster development of male than female embryos in vitro. Two genes located on the X chromosome, glucose-6-phosphate dehydrogenase (G6PD) and hypoxanthine phosphoribosyl transfer