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Comparison of Four-Drug Regimens and Pairs of Sequential Three-Drug Regimens as Initial Therapy for HIV-1 Infection

โœ Scribed by Shafer, Robert W.; Smeaton, Laura M.; Robbins, Gregory K.; De Gruttola, Victor; Snyder, Sally W.; D'Aquila, Richard T.; Johnson, Victoria A.; Morse, Gene D.; Nokta, Mostafa A.; Martinez, Ana I.; Gripshover, Barbara M.; Kaul, Pamposh; Haubrich, Richard; Swingle, Mary; McCarty, S. Debra; Vella, Stefano; Hirsch, Martin S.; Merigan, Thomas C.


Book ID
126789584
Publisher
Massachusetts Medical Society
Year
2003
Tongue
English
Weight
179 KB
Volume
349
Category
Article
ISSN
0096-6762

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## Abstract Therapy failure due to drug resistance development is a common phenomenon in HIVโ€infected patients. However, when the drug pressure leads to the earliest selection of drugโ€resistant HIVโ€1 populations is still unclear. In this study, the extent to which selection of the HIVโ€1 reverse tra