The purpose of this study was to correlate the abnormal signal area on various magnetic resonance (MR) images to the infarct area on pathologic examination and to assess the myocardial viability on the basis of MR images. T2weighted, first-pass perfusion, and delayed gadolinium-enhanced T1-weighted
Comparison of first-pass Gd-DOTA and FAIRER MR perfusion imaging in a rabbit model of pulmonary embolism
✍ Scribed by Shella D. Keilholz; Vu M. Mai; Stuart S. Berr; Naomi Fujiwara; Klaus D. Hagspiel
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 315 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Purpose
To compare the sensitivity of contrast‐enhanced magnetic resonance imaging (MRI) and arterial spin labeling to perfusion deficits in the lung.
Materials and Methods
A rabbit model of pulmonary embolism was imaged with both flow‐sensitive alternating inversion recovery with an extra radiofrequency pulse (FAIRER) arterial spin labeling and Gd‐DOTA enhanced MRI. The signal‐to‐noise ratio (SNR) was measured in the area of the perfusion deficit and the normal lung for both techniques.
Results
The defect was readily visible in all images. The normal lung had an average of 3.8 ± 1.2 times the SNR of the unperfused lung with the arterial spin labeling technique, and approximately 13.7 ± 3.3 times the SNR with the contrast‐enhanced technique.
Conclusion
Gd‐DOTA enhanced MRI provides higher SNR in pulmonary perfusion imaging; however, arterial spin labeling is also adequate and may be used when repeated studies are indicated. J. Magn. Reson. Imaging 2002;16:168–171. © 2002 Wiley‐Liss, Inc.
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