Comparison of enzyme immunoassay and dextran-coated charcoal techniques for progesterone receptor determination in human breast cancer cytosols
โ Scribed by John A. Foekens; Henk Portengen; Jolie van Driel; Wim L.J. van Putten; Willem G. Haije; Jan G.M. Klijn
- Book ID
- 116007146
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 364 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-4731
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Biopsy specimens from 106 women with primary operable, recurrent or metastatic breast cancer were analyzed in a double blind study designed to compare the results of a new fluorescent antibody method for detection of estrogen receptors with estrogen receptors measured biochemically with dextran-coat
Most investigators comparing ligand-binding procedures for quantifying estrogen and progestin receptors in human breast cancer with procedures employing monoclonal antibodybased methods have utilized an inappropriate variety of reaction conditions, including the elimination of sodium molybdate in th
Evaluation of estrogen (ER) and progesterone (PR) receptor content is now an important procedure in the management of breast cancer patients. Production of monoclonal antibodies to ER and PR has permitted development of an enzyme immunoassay (EIA) and immunocytochemical assay (ICA). This study compa