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Comparison of enzymatic and pharmacological activities of lysine-49 and aspartate-49 phospholipases A2 from Agkistrodon piscivorus piscivorus snake venom

✍ Scribed by Daljit S. Dhillon; Eleonora Condrea; John M. Maraganore; Robert L. Heinrikson; Sheila Benjamin; Philip Rosenberg


Book ID
115779446
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
877 KB
Volume
36
Category
Article
ISSN
0006-2952

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Trimeresurus fivoviridis (Habu snake) venom aspartate-49-phospholipase A2 (Asp-49-PLAz) was reacted at pH 9.0 with a 2-fold molar excess of 2,4,6-trinitrobenzenesdfonate in the absence of Ca" and two trinitrophenylated derivatives were isolated by HPLC. One was a derivative modified at Lys-11 and it