𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats

✍ Scribed by Brian C. Cooley; Mark M. Jones; Dr. A. Lee Dellon

Book ID
102511544
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
298 KB
Volume
4
Category
Article
ISSN
0738-1085

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✦ Synopsis

A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.

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Catheter-based local thrombolysis with u
Catheter-based local thrombolysis with urokinase: Comparative efficacy of intraluminal clot lysis with conventional urokinase infusion techniques in an in vivo porcine thrombus model
✍ Mitchel, Joseph F. ;Shwedick, Michael ;Alberghini, Tod A. ;Knibbs, David ;McKay, πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 164 KB

Local delivery of urokinase directly to the site of intraluminal clot using catheter-based technology has recently been introduced as a new technique to treat intracoronary thrombus and thrombus-containing stenoses. The purpose of this study was to compare the efficacy of urokinase therapy administe