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Comparison of doxorubicin-induced DNA damage in doxorubicin-sensitive and -resistant P388 murine leukemia cells

✍ Scribed by Giovanni Capranico; Teresa Dasdia; Franco Zunino


Publisher
John Wiley and Sons
Year
1986
Tongue
French
Weight
465 KB
Volume
37
Category
Article
ISSN
0020-7136

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## Abstract HL‐60‐R, a multi‐drug‐resistant (MDR) subclone of the human leukemia cell line HL‐60, was selected in continuous culture in doxorubicin (DOX) in the absence of mutagenic agents. When compared to the parent line HL‐60, HL‐60‐R showed greater relative resistance to vinblastine than to eto