Improved synthesis of DOTA tetraamide li
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Luis M. De León-Rodríguez; Subha Viswanathan; A. Dean Sherry
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Article
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2010
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John Wiley and Sons
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English
⚖ 165 KB
The synthesis of new DOTA tetraamide (DOTAMR 4 ) compounds is of great interest given their application in the formation of Ln(III) complexes as potential PARACEST contrast agents in MRI or fluorescent molecular probes. In this context amino acid and peptide DOTAMR 4 derivatives are particularly att