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Comparison of different activators and diazotization procedures in the assay of bilirubin-UDP-glucuronyl transferase activity in rat liver

โœ Scribed by Nicola Tavoloni; Mary Jane T. Jones; Robert Wittman; Kiang Chih-Li; Paul D. Berk

Book ID
115824457
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
930 KB
Volume
128
Category
Article
ISSN
0009-8981

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The presence of a microsomal UDP-glucuro
The presence of a microsomal UDP-glucuronyl transferase for bilirubin in homozygous jaundiced gunn rats and in the crigler-najjar syndrome
โœ Gerard B. Odell; Julio O. Cukier; Glenn R. Gourley ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 962 KB

The infusion of a closely related derivative of bilirubin, its dimethyl diester (DME), into jaundiced (jj) Gunn rats was associated with biliary excretion of mono-and diglucuronides of bilirubin. In uitro incubation of DME with liver microsomes from jj rats demonstrated sequential demethylation and