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Comparison of daunorubicin and anthrapyrazolone sensitivity and transport in resistant cell lines

✍ Scribed by McGown, A; Poppitt, DG; Fox, BW


Book ID
109835883
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
588 KB
Volume
56
Category
Article
ISSN
0007-0920

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We developed three daunorubicin (D1)-resistant sublines (ML1/I, II, III) from the human myelocytic cell line (ML1). These sublines were 28-, 70- and 162-fold more resistant than sensitive (ML1/S) cells to the cytotoxicity of D1 and were cross-resistant to adriamycin, epiadriamycin, actinomycin D, VP