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Comparison of chromosomal aberrations detected by fluorescence in situ hybridization with clinical parameters, DNA ploidy and Ki 67 expression in renal cell carcinoma

✍ Scribed by Igawa, M; Shiina, H; Shigeno, K; Yokogi, H; Urakami, S; Yoneda, T; Maruyama, R; Wada, Y

Book ID: 109837539
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 819 KB
Volume: 77
Category: Article
ISSN: 0007-0920
DOI: 10.1038/bjc.1998.332

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## Background: A fluorescence in situ hybridization (fish) technique using specific dna probes allows for the detection of chromosomal aberrations and gene deletions and gains, even in interphase nuclei in human solid tumors. a high frequency of aberrations of chromosome 17 and mutation of the p53