Women with single, viable pregnancies at 10+5 to 13+6 weeks' gestation who requested fetal karyotyping for maternal age, parental anxiety, or a previous history of chromosomal aberration were offered participation in this study. With a transabdominal ultrasound-guided technique, early amniocentesis
โฆ LIBER โฆ
Comparison of chorionic villus sampling and amniocentesis for fetal karyotyping at 10-13 weeks' gestation
โ Scribed by K Nicolaides; MdeL Brizot; F Patel; R Snijders
- Book ID
- 118555699
- Publisher
- The Lancet
- Year
- 1994
- Tongue
- English
- Weight
- 592 KB
- Volume
- 344
- Category
- Article
- ISSN
- 0140-6736
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In 42 cases of trisomy 13 at 10ยฑ14 weeks of gestation, compared with 947 controls, the median multiple of the median (MoM) of maternal serum free b-human chorionic gonadotrophin (b-hCG) and pregnancy associated plasma protein A (PAPP-A) was signiยฎcantly decreased (0.506 MoM and 0.248 MoM respectivel