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Comparison of bopindolol and atenolol in chronic stable angina pectoris

โœ Scribed by P. Fitscha; W. Meisner; B. Tiso


Publisher
Springer
Year
1990
Tongue
English
Weight
350 KB
Volume
38
Category
Article
ISSN
0031-6970

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โœฆ Synopsis


The efficacy of bopindolol and atenolol in the treatment of patients with chronic stable angina pectoris have been compared in a double blind, randomized study. Both bopindolol 1 mg and atenolol 100 mg for 6 weeks increased mean exercise time (25% and 22%, respectively, compared to placebo), time to angina (27% and 25%), and time to 1 mm of ST-segment depression (32% and 20%). Both drugs reduced ST-segment depression similarly at maximal and submaximal work levels. There was no significant difference in their antianginal efficacy.


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โœ Vivian F. Challenor; Derek G. Waller; Charles F. George ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer US ๐ŸŒ English โš– 968 KB

The antianginal effects ofbeta-adrenoceptor antagonists are achieved by a reduction in myocardial oxygen demand. This is a rational approach to treatment in patients whose angina is caused by a fixed stenosis. However, dynamic coronary vasospasm is an important factor in patients with chronic stable