Comparison of bone age delay and recovery in Meyer dysplasia and Legg-Calvé-Perthes disease: a pilot study

Age at onset–dependent presentations of

Age at onset–dependent presentations of premature hip osteoarthritis, avascular necrosis of the femoral head, or Legg-Calvé-Perthes disease in a single family, consequent upon a p.Gly1170Ser mutation of COL2A1

✍ Peiqiang Su; Ru Li; Shangli Liu; Yan Zhou; Xinguang Wang; Nilesh Patil; Christop 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 2 views

## Abstract ## Objective To identify the genetic abnormality responsible for osteoarthritis (OA), avascular necrosis (AVN) of the femoral head, and Legg‐Calvé‐Perthes disease in a single family, and to determine factors responsible for the distinct phenotypes manifested by different family members