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Comparison of bile acid binding to sinusoidal and bile canalicular membranes isolated from rat liver

✍ Scribed by Kiyoto Yachi; Yuichi Sugiyama; Tatsuji Iga; Yusei Ikeda; Gotaro Toda; Manabu Hanano


Book ID
115728113
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
672 KB
Volume
901
Category
Article
ISSN
0005-2736

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To study the effect of bile acids on P-glycoproteinmediated drug transport, we performed experiments using multidrug resistant cells and rat canalicular membrane vesicles. Cellular accumulation and efflux of rhodamine 123 were measured in drug-resistant cells by means of computerized quantitative im