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Comparison of Bidirectional Cephalexin Transport Across MDCK and Caco-2 Cell Monolayers: Interactions with Peptide Transporters

✍ Scribed by Wendy S. Putnam; Lin Pan; Ken Tsutsui; Lori Takahashi; Leslie Z. Benet

Book ID
110323070
Publisher
Springer US
Year
2002
Tongue
English
Weight
233 KB
Volume
19
Category
Article
ISSN
0724-8741

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Bidirectional transport studies were conducted using Caco-2, MDCK, and MDCK-MDR1 to determine P-gp influences in lamivudine and zidovudine permeability and evaluate if zidovudine permeability changes with the increase of zidovudine concentration and/or by association of lamivudine. Transport of lami