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Comparison of autologous stem cell transplantation versus consolidation chemotherapy for patients with cytogenetically normal acute myeloid leukemia (CN-AML) and FLT3ITD

✍ Scribed by Harshabad Singh; Lillian L. Werner; Salma Asali; Daniel J. DeAngelo; Karen K. Ballen; Philip C. Amrein; Martha Wadleigh; Ilene Galinsky; Brian Wolpin; Joseph Pidala; Donna S. Neuberg; Edward A. Fox; Richard M. Stone; Eyal C. Attar

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 659 KB
Volume: 86
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.22041

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Myeloablative chemotherapy followed by autologous stem cell infusion may overcome the adverse prognostic impact of FLT3 (foetal liver tyrosine kinase 3) mutations in patients with acute myeloid leukaemia and normal karyotype

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## Abstract In this study, we analysed the prognostic relevance of foetal liver tyrosine kinase 3 (FLT3) mutations in 73 patients with acute myeloid leukaemia (AML) with normal karyotype, who survived induction and consolidation and received autologous stem cell transplantation (ASCT) after success