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Comparison of approaches for efficient gene silencing induced by microRNA-based short hairpin RNA and indicator gene expression

โœ Scribed by Z. X. Shan; Q. X. Lin; C. Y. Deng; Z. L. Zhou; H. H. Tan; Y. H. Fu; X. H. Li; J. N. Zhu; L. P. Mai; S. J. Kuang; S. G. Lin; X. Y. Yu


Book ID
106470053
Publisher
Springer
Year
2009
Tongue
English
Weight
414 KB
Volume
37
Category
Article
ISSN
0301-4851

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Vector-based RNA interference (RNAi) has attracted great interest, because of its more prolonged gene silencing effect compared with small interfering RNA (siRNA). However, the intensity and duration of vector-based RNAi effect has received little attention. In this study, the gene silencing kinetic