To improve the sensitivity of the radioimmunoassay method for anti-AChR-antibody, large amounts of sera from patients with myasthenia gravis, and higher concentrations of antigens and rabbit anti-human-IgG-antiserum, were used. These procedures enabled measurement of the titre value of over 0.04 pmo
β¦ LIBER β¦
Comparison of antibody titer to human and rat acetylcholine receptor in myasthenia gravis
β Scribed by Masatoshi Hayashi; Tomohiko Takaoka; Kohji Manabe; Junji Yoshinaga; Kaichi Kida
- Book ID
- 116137213
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 286 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0387-7604
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## Abstract Aspects of acetylcholine receptor immunology and circulating receptor antibodies are reviewed with regard to both human and experimental myasthenia gravis. Receptor antibodies that have negligible crossβreactivity with skeletal muscle receptor can nonetheless cause destruction of the po