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Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene

✍ Scribed by Zhiying Ji; Rosana H. Weldon; Francesco Marchetti; Howard Chen; Guilan Li; Caihong Xing; Elaine Kurtovich; Suzanne Young; Thomas E. Schmid; Suramya Waidyanatha; Stephen Rappaport; Luoping Zhang; Brenda Eskenazi

Book ID
112083505
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
793 KB
Volume
53
Category
Article
ISSN
0893-6692

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Benzene increases aneuploidy in the lymp
Benzene increases aneuploidy in the lymphocytes of exposed workers: A comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells
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Benzene is an established human leukemogen that increases the level of chromosome aberrations in lymphocytes of exposed workers. Numerical aberrations (aneusomy) can be observed by fluorescence in situ hybridization (FISH) in both interphase and metaphase cells. Whereas interphase FISH allows nondiv