Comparing the disease modifying effects of alendronate to risedronate in the rat anterior cruciate ligament transection model of osteoarthritis
β Scribed by Hayami, T.; Wesolowski, G.; Ya, Z.; Pickarski, M.; Duong, L.T.
- Book ID
- 122165177
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 49 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1063-4584
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## Objective: It has been suggested that subchondral bone remodeling plays a role in the progression of osteoarthritis (oa). to test this hypothesis, we characterized the changes in the rat anterior cruciate ligament transection (aclt) model of oa and evaluated the effects of alendronate (aln), a p
## Abstract Transection of the anterior cruciate ligament in the dog leads to osteoarthritis. This study defines the kinematic changes in the unstable knee after transection of the cruciate ligament (six dogs) and after a sham operation (four dogs). In the dogs that were anterior cruciate ligamentβ