Comparing metabolic network models based on genomic and automatically inferred enzyme information from Plasmodium and its human host to define drug targets in silico

Comparing metabolic network models based

Comparing metabolic network models based on genomic and automatically inferred enzyme information from Plasmodium and its human host to define drug targets in silico

✍ Segun Fatumo; Kitiporn Plaimas; Ezekiel Adebiyi; Rainer König 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 379 KB

Plasmodium falciparum causes the most severe malaria pathogen and has developed resistance to existing drugs making it indispensable to discover new drugs. In order to predict drug targets in silico, a useful model for the metabolism is needed. However, automatically reconstructed network models typ