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Comparing antibody and small-molecule therapies for cancer

✍ Scribed by Imai, Kohzoh; Takaoka, Akinori


Book ID
109947652
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
434 KB
Volume
6
Category
Article
ISSN
1474-1776

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## Abstract A critical regulator of the apoptotic machinery is the Bcl‐2 family proteins whose over expression confers a protective effect on malignant cells against death signals of apoptosis. Cancer cells that are resistant to various anti‐cancer drugs and treatment regimen are found to over expr