Structural basis for the biological acti
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Etsuko Katoh; Hideki Nishio; Tatsuya Inui; Yuji Nishiuchi; Terutoshi Kimura; Shu
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Article
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2000
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Wiley (John Wiley & Sons)
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English
โ 389 KB
๐ 2 views
A topochemical model to explain the biological activity of dendrotoxin-I (DTX-I), a potent blocker for potassium channels, was developed by searching common spatial arrangements of functionally important residues between DTX-I, alpha-dendrotoxin, dendrotoxin-K, BgK, ShK, and charybdotoxin. The first