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Comparativeβ-adrenoceptor blocking effect and pharmacokinetics of bucindolol and propranolol in man

✍ Scribed by M. Maury; A. Berdeaux; A. Kher; P. Duhaze; J. F. Giudicelli

Publisher
Springer
Year
1985
Tongue
English
Weight
720 KB
Volume
27
Category
Article
ISSN
0031-6970

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l-bunolol and propranolol: Oral and intr
l-bunolol and propranolol: Oral and intravenous β-adrenoceptor blocking activity in rats compared to dogs and humans
✍ H. R. Kaplan; M. A. Commarato; E. C. Lattime 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB

To determine the pharmacological significance of reported differences between species in l-bunolol metabolism, oral and intravenous beta-adrenoceptor blocking activity against an isoproterenol-induced tachycardia was compared in dogs, rats, and humans. Propranolol was similarly studied in rats and d