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Comparative Toxicokinetics of Inhaled Methanol in the Female CD-1 Mouse and Sprague-Dawley Rat

✍ Scribed by Robert A. Perkins; Keith W. Ward; Gary M. Pollack


Book ID
115608546
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
596 KB
Volume
28
Category
Article
ISSN
0272-0590

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Exposure of pregnant CD-1 mice to methanol (MeOH) by inhalation on gestation days (gd) 6-15 results in dose-related increases in fetal cleft palate, exencephaly, and skeletal defects. Here, critical periods for the developmental toxicity of MeOH were assessed in pregnant CD-1 mice exposed to 10,000