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Comparative toxicity of (+)-(R)- and (−)-(S)-1,2-dibromo-3-chloropropane

✍ Scribed by Samir A. Kouzi; Erik J. Søderlund; Erik Dybing; John H. N. Meerman; Sidney D. Nelson


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
551 KB
Volume
7
Category
Article
ISSN
0899-0042

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The organ-specific toxic potency of subcutaneously administered 1,2-dibromo-3-chloropropane (DBCP) was compared in partially hepatectomized and sham-operated rats over a dose range of 20-80 mg kg-' to assess the roles of hepatic and extrahepatic metabolism in protection against acute renal and gonad