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Comparative study of smoke condensates from 1R4F cigarettes that burn tobacco versus ECLIPSE cigarettes that primarily heat tobacco in the SENCAR mouse dermal tumor promotion assay

โœ Scribed by Daniel R. Meckley; Johnnie R. Hayes; K.R. Van Kampen; Paul H. Ayres; Arnold T. Mosberg; James E. Swauger


Book ID
116461200
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
323 KB
Volume
42
Category
Article
ISSN
0278-6915

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The genotoxic potential of mainstream smoke from a test cigarette (TOB-HT) that primarily heats tobacco and a representative tobacco-burning cigarette (Kentucky reference 1R4F) was compared in male B6C3/F1 mice after nose-only inhalation exposure. Mice were exposed 1 hr per day, 5 days/ week for a 4