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Comparative Study of Catalytic (DNA-Hydrolyzing) and Cytotoxic Properties of Anti-DNA Autoantibodies

✍ Scribed by S.V. Suchkov


Book ID
110365727
Publisher
Springer US
Year
2001
Tongue
English
Weight
473 KB
Volume
131
Category
Article
ISSN
0007-4888

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## Abstract Autoantibodies that bind DNA are a hallmark of systemic lupus erythematosus. A subset of autoantibodyβ€’DNA complexes localize to kidney tissue and lead to damage and even death. 11F8, 9F11, and 15B10 are clonally related anti‐DNA autoantibodies isolated from an autoimmune mouse. 11F8 bin