Comparative study between intravenous and subcutaneous administration of cladribine in treatment of hairy cell leukemia patients
β Scribed by Nehad M. Tawfik, Aml Soliman Nasr
- Book ID
- 118788015
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 165 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1618-5641
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## Abstract ## BACKGROUND. The purine analogs pentostatin and cladribine have revolutionized the treatment of hairy cell leukemia (HCL) with overall responses in greater than 85% of patients and a median progressionβfree survival of up to 15 years. They continue to be effective at secondβ and even
## Background: Deoxycoformycin (dcf) has been reported to produce high response rates in patients with hairy cell leukemia (hcl), but to the authors' knowledge data regarding experience with such therapy in a large hcl series are scarce. ## Methods: Between 1988-1997, dcf (4 mg/m(2)/day, every 2