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Comparative studies of leukemic cells sensitive and resistant to cytosine arabinoside

✍ Scribed by M.Y. Chu; G.A. Fischer


Book ID
115768971
Publisher
Elsevier Science
Year
1965
Tongue
English
Weight
726 KB
Volume
14
Category
Article
ISSN
0006-2952

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Quantitation of resistance of leukemic c
✍ F. Lacombe; F. Belloc; P. Dumain; M. Puntous; F. Lopez; P. Bernard; M. R. Boisse πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 783 KB

The cytotoxicity of ara-C derives from an inhibition of DNA synthesis after incorporation of ara-CTP into DNA. The rate of DNA synthesis can be determined from the amount of bromodeoxy-uridine (BrdUrd) incorporated into cells after a short exposure to BrdUrd. We developed a computer program to quant