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Comparative structure and characterization of a CDKN2 gene in a Xiphophorus fish melanoma model

โœ Scribed by Kazianis, S; Morizot, D C; Della Coletta, L; Johnston, D A; Woolcock, B; Vielkind, J R; Nairn, R S


Book ID
110062292
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
426 KB
Volume
18
Category
Article
ISSN
0950-9232

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โœ Steven Kazianis; Heidrun Gutbrod; Rodney S. Nairn; Brenda B. McEntire; Luis Dell ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 175 KB

The Xiphophorus hybrid melanoma model represents one of the earliest reported cases of genetically regulated tumor susceptibility. Melanoma formation in Xiphophorus hybrids may be explained by the inheritance of two genes: a sex-linked oncogene, Xmrk, and a putative tumor suppressor locus, termed DI