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Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7α-hydroxylase activities in the rat, guinea pig, and rabbit: Effects of cholesterol and bile acids

✍ Scribed by Lien B. Nguyen; Guorong Xu; Sarah Shefer; G.Stephen Tint; Ashok Batta; Gerald Salen


Book ID
117180933
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
816 KB
Volume
48
Category
Article
ISSN
1532-8600

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We examined the effects of feeding deoxycholic acid (1% and 0.4% of diet), alone and in combination with ursodeoxycholic acid, on serum and biliary bile acid concentrations, hepatic morphology, and the activities and steady-state messenger RNA (mRNA) levels of HMG-CoA reductase and cholesterol 7a-hy