The function of a protein is generally determined by its three-dimensional (3D) structure. Thus, it would be useful to know the 3D structures of the thousands of protein sequences that are emerging from the many genome projects. This is the aim of structural genomics. The aim will be achieved by a f
COMPARATIVE PROTEIN STRUCTURE MODELING OF GENES AND GENOMES
✍ Scribed by Martí-Renom, Marc A.; Stuart, Ashley C.; Fiser, András; Sánchez, Roberto; Melo, Francisco; Šali, Andrej
- Book ID
- 111681098
- Publisher
- Annual Reviews
- Year
- 2000
- Tongue
- English
- Weight
- 352 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1056-8700
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We evaluate homology-derived 3D models of dihydrofolate reductase (DFR 1 ), phosphotransferase enzyme IIA domain (PTE2A 3 ), and mouse/human UBC9 protein (UBC9 24 ) which were submitted to the second Meeting on the Critical Assessment of Techniques for Protein Structure Prediction (CASP). The DFR 1
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