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Comparative pharmacokinetics of vindesine, vincristine and vinblastine in patients with cancer

✍ Scribed by Nelson, R.L.; Dyke, R.W.; Root, M.A.

Book ID
123126014
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
600 KB
Volume
7
Category
Article
ISSN
0305-7372

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The comparative clinical pharmacology an
The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer
✍ Nelson, Robert L. πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 603 KB

## Abstract The pharmacokinetics of vindesine, vincristine, and vinblastine were investigated in patients with cancer. All drugs were administered rapidly via intravenous injection, and drug levels were determined in serum obtained at intervals after injection by radioimmunoassay. All three drugs e

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Pharmacokinetics of vincristine, vinblastine, and vindesine in rhesus monkeys
✍ V. Sagar Sethi; Paulette Surratt; Charles L. Spurr πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 494 KB

The pharmacokinetics of vincristine, vindesine, and vinblastine following IV bolus doses of 0.05 rag, 0.10 rag, and 0.20 mg/kg body weight, respectively, were studied in adult male rhesus monkeys. The alkaloid concentrations were determined by a sensitive radioimmunoassay. Pharmacokinetic data were