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Comparative pharmacokinetics of medroxyprogesterone acetate administered by oral and intramuscular routes

✍ Scribed by M. Salimtschik; H. T. Mouridsen; J. Loeber; E. Johansson


Book ID
112286029
Publisher
Springer
Year
1980
Tongue
English
Weight
270 KB
Volume
4
Category
Article
ISSN
0344-5704

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A single intramuscular (IM) dose of 50 mg amitriptyline (AT) was given to each of two healthy subjects who had previously taken three oral doses of AT tablets. The concentration-time curves of plasma nortriptyline (NT) arising from IM AT were fitted by computer to an equation based on the assumption